Slc24a5^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slc24a5^tm1Lex
• Name: solute carrier family 24, member 5; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3776796
• Gene: Slc24a5 Location: Chr2:124910076-124930316 bp, + strand Genetic Position: Chr2, 61.14 cM
• Alliance: Slc24a5^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137416
• Parent Cell Line: Lex-2 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A betageo/Puro selection cassette replaced a 784 bp region containing coding exons 3-5. (J:137416)

Disease models

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc24a5 Mutation: 31 strains or lines available

References

• Original: J:137416 Vogel P, et al., Ocular albinism and hypopigmentation defects in Slc24a5-/- mice. Vet Pathol. 2008 Mar;45(2):264-79
• All: 1 reference(s)