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Kng1tm1Krmc
Targeted Allele Detail
Nomenclature
Symbol: Kng1tm1Krmc
Name: kininogen 1; targeted mutation 1, Keith R McCrae
MGI ID: MGI:3776034
Gene: Kng1  Location: Chr16:23057865-23082068 bp, + strand  Genetic Position: Chr16, 13.88 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130769
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 10 was replaced with a floxed neo cassette. The absence of protein product was confirmed by western blot analysis on plasma. (J:130769)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kng1 Mutation:  31 strains or lines available
References
Original:  J:130769 Merkulov S, et al., Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis. Blood. 2008 Feb 1;111(3):1274-81
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory