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Targeted Allele Detail
Symbol: Efemp1tm2Lmar
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 1; targeted mutation 2, Lihua Y Marmorstein
MGI ID: MGI:3776015
Gene: Efemp1  Location: Chr11:28853204-28926743 bp, + strand  Genetic Position: Chr11, 16.32 cM, cytoband A4
Germline Transmission:  Earliest citation of germline transmission: J:132043
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 4 and 5 were replaced with a floxed neo cassette. The absence of protein product was confirmed by western blot analysis on lung extracts. (J:132043)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Efemp1 Mutation:  5 strains or lines available
Original:  J:132043 McLaughlin PJ, et al., Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice. Hum Mol Genet. 2007 Dec 15;16(24):3059-70
All:  3 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.01
The Jackson Laboratory