Sicd4^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Sicd4^DBA/2J
• Name: seizure-induced cell death 4; DBA/2J
• MGI ID: MGI:3775638
• QTL: Sicd4 Location: Chr18:69805276-85514143 bp Genetic Position: Chr18, Syntenic

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: This allele confers susceptibility to hippocampal cell death caused by kainic acid-induced seizures compared to C57BL/6J. (J:132288)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

References

• Original: J:132288 McLin JP, et al., Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid. Neurobiol Dis. 2008 Mar;29(3):391-9
• All: 1 reference(s)