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Tg(Vil1-CYP3A4)1Nki
Transgene Detail
Nomenclature
Symbol: Tg(Vil1-CYP3A4)1Nki
Name: transgene insertion 1, The Netherlands Cancer Institute
MGI ID: MGI:3775624
Transgene: Tg(Vil1-CYP3A4)1Nki  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
    The mouse villin promoter was used to drive expression of human CYP3A4 in the small intestine. (J:127366)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:127366 van Herwaarden AE, et al., Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J Clin Invest. 2007 Nov;117(11):3583-92
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory