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FlnbGt(RRF239)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: FlnbGt(RRF239)Byg
Name: filamin, beta; gene trap RRF239, BayGenomics
MGI ID: MGI:3775521
Synonyms: Flnb-
Gene: Flnb  Location: Chr14:7817957-7951588 bp, + strand  Genetic Position: Chr14, 4.59 cM
Mutation
origin
Mutant Cell Line:  RRF239 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:132026
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation details
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 21 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Flnb Mutation:  100 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References
Original:  J:132026 Farrington-Rock C, et al., Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome. Hum Mol Genet. 2008 Mar 1;17(5):631-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory