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Foxa2tm2.1(cre/Esr1*)Moon
Targeted Allele Detail
Nomenclature
Symbol: Foxa2tm2.1(cre/Esr1*)Moon
Name: forkhead box A2; targeted mutation 2.1, Anne M Moon
MGI ID: MGI:3774420
Synonyms: Foxa2Cre-ER, Foxa2creERT2, Foxa2mcm, Foxa2tm2.1(cre/Esr1)Moon
Gene: Foxa2  Location: Chr2:148042877-148046969 bp, - strand  Genetic Position: Chr2, 73.38 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130990
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsThe neo cassette in Foxa2tm2(cre/Esr1*)Moon was removed by germ-line, flp-mediated recombination. Expression of transcript was confirmed by in situ hybridization. (J:130990)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxa2     Summary of all recombinase alleles driven by Foxa2. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxa2 Mutation:  21 strains or lines available
References
Original:  J:130990 Park EJ, et al., System for tamoxifen-inducible expression of cre-recombinase from the Foxa2 locus in mice. Dev Dyn. 2008 Feb;237(2):447-53
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory