Eomes^tm1.1Whk
Targeted Allele Detail

Summary

• Symbol: Eomes^tm1.1Whk
• Name: eomesodermin; targeted mutation 1.1, William H Klein
• MGI ID: MGI:3774148
• Synonyms: Eomes^deltaflox
• Gene: Eomes Location: Chr9:118307259-118315176 bp, + strand Genetic Position: Chr9, 70.21 cM, cytoband F3
• Alliance: Eomes^tm1.1Whk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130570
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 was removed by germ-line, cre-mediated recombination. Authors state that this is a null allele. (J:130570)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eomes Mutation: 41 strains or lines available

References

• Original: J:130570 Mao CA, et al., Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development. 2008 Jan;135(2):271-80
• All: 1 reference(s)