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Asphtm1Egk
Targeted Allele Detail
Nomenclature
Symbol: Asphtm1Egk
Name: aspartate-beta-hydroxylase; targeted mutation 1, Evangelia G Kranias
MGI ID: MGI:3774139
Synonyms: Jct-
Gene: Asph  Location: Chr4:9448069-9669344 bp, - strand  Genetic Position: Chr4, 4.17 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130155
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on heart extracts. (J:130155)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asph Mutation:  34 strains or lines available
References
Original:  J:130155 Yuan Q, et al., Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity. Circulation. 2007 Jan 23;115(3):300-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory