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Alkbh1tm1.1Lpkn
Targeted Allele Detail
Nomenclature
Symbol: Alkbh1tm1.1Lpkn
Name: alkB homolog 1, histone H2A dioxygenase; targeted mutation 1.1, Steven M Lipkin
MGI ID: MGI:3774031
Synonyms: Alkbh1-
Gene: Alkbh1  Location: Chr12:87428077-87443839 bp, - strand  Genetic Position: Chr12, 41.65 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131022
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 3 was removed by germ-line, cre-mediated recombination. The absence of protein product was confirmed by western blot analysis. (J:131022)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Alkbh1 Mutation:  11 strains or lines available
References
Original:  J:131022 Pan Z, et al., Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice. Dev Dyn. 2008 Feb;237(2):316-27
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory