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Xbp1tm2Glm
Targeted Allele Detail
Nomenclature
Symbol: Xbp1tm2Glm
Name: X-box binding protein 1; targeted mutation 2, Laurie H Glimcher
MGI ID: MGI:3774017
Synonyms: XBP-1flox
Gene: Xbp1  Location: Chr11:5520659-5525893 bp, + strand  Genetic Position: Chr11, 3.61 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131028
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Cre-mediated recombination of Xbp1tm3Glm removed the neo cassette and left exon 2 floxed. (J:131028)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xbp1 Mutation:  7 strains or lines available
References
Original:  J:131028 Hetz C, et al., Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):757-62
All:  64 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory