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Targeted Allele Detail
Symbol: Foxc1tm1Tsku
Name: forkhead box C1; targeted mutation 1, Tsutomu Kume
MGI ID: MGI:3773756
Synonyms: Foxc1flx
Gene: Foxc1  Location: Chr13:31806691-31810643 bp, + strand  Genetic Position: Chr13, 13.52 cM
Germline Transmission:  Earliest citation of germline transmission: J:131323
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted upstream of the coding sequence. An additional loxP site was inserted downstream of the coding sequence. Flp-mediated recombination removed the neo cassette. (J:188816)
Generation of the Foxc1tm1Tsku and Foxc1tm1.1Tsku alleles
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc1 Mutation:  9 strains or lines available
Original:  J:131323 Hayashi H, et al., Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration. Biochem Biophys Res Commun. 2008 Mar 14;367(3):584-9
All:  9 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.03
The Jackson Laboratory