Stk36^tm1.1Ptch
Targeted Allele Detail

Summary

• Symbol: Stk36^tm1.1Ptch
• Name: serine/threonine kinase 36; targeted mutation 1.1, Pao-Tien Chuang
• MGI ID: MGI:3773685
• Synonyms: Fu^-, Fu^deltaE1-5
• Gene: Stk36 Location: Chr1:74640604-74676053 bp, + strand Genetic Position: Chr1, 38.54 cM, cytoband C3
• Alliance: Stk36^tm1.1Ptch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131268
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Chimeric males with the floxed region were crossed to cre-expressing females and exons 1 through 5 were removed in the germ line. The absence of transcript was confirmed by northern blot analysis on E10.5 embryos extracts. (J:131268)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk36 Mutation: 50 strains or lines available

References

• Original: J:131268 Chen MH, et al., Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development. Mol Cell Biol. 2005 Aug;25(16):7042-53
• All: 5 reference(s)