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Ptgdr2tm1Tasa
Targeted Allele Detail
Nomenclature
Symbol: Ptgdr2tm1Tasa
Name: prostaglandin D2 receptor 2; targeted mutation 1, Takahiro Satoh
MGI ID: MGI:3773068
Synonyms: CRTH2-, Gpr44-
Gene: Ptgdr2  Location: Chr19:10937160-10942511 bp, + strand  Genetic Position: Chr19, 7.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131146
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe third coding region was replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on lung extracts. (J:131146)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptgdr2 Mutation:  2 strains or lines available
References
Original:  J:131146 Satoh T, et al., Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor. J Immunol. 2006 Aug 15;177(4):2621-9
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory