Ramp2^tm1Tash
Targeted Allele Detail

Summary

• Symbol: Ramp2^tm1Tash
• Name: receptor (calcitonin) activity modifying protein 2; targeted mutation 1, Takayuki Shindo
• MGI ID: MGI:3773018
• Synonyms: floxed RAMP2
• Gene: Ramp2 Location: Chr11:101137160-101139076 bp, + strand Genetic Position: Chr11, 64.47 cM
• Alliance: Ramp2^tm1Tash page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130931
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A neo cassette with a 3' loxP site was inserted into intron 4 and an additional loxP site was inserted into intron 1. (J:130931)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ramp2 Mutation: 16 strains or lines available

References

• Original: J:130931 Ichikawa-Shindo Y, et al., The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity. J Clin Invest. 2008 Jan;118(1):29-39
• All: 7 reference(s)