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Kcnd3tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Kcnd3tm1Dgen
Name: potassium voltage-gated channel, Shal-related family, member 3; targeted mutation 1, Deltagen
MGI ID: MGI:3772775
Synonyms: Kv4.3-
Gene: Kcnd3  Location: Chr3:105452330-105674002 bp, + strand  Genetic Position: Chr3, 46.32 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130722
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv x C57BL/6
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 replaced with a lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on brain extracts. (J:130722)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnd3 Mutation:  1 strain or line available
References
Original:  J:130722 Niwa N, et al., Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles. J Mol Cell Cardiol. 2008 Jan;44(1):95-104
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory