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Lhx2tm1Monu
Targeted Allele Detail
Nomenclature
Symbol: Lhx2tm1Monu
Name: LIM homeobox protein 2; targeted mutation 1, Edwin S Monuki
MGI ID: MGI:3772179
Synonyms: Lhx2cKO, Lhx2lox
Gene: Lhx2  Location: Chr2:38229293-38259745 bp, + strand  Genetic Position: Chr2, 24.31 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130167
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted into intron 3 and an additional loxP site was inserted into intron 1. (J:130167)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx2 Mutation:  10 strains or lines available
References
Original:  J:130167 Mangale VS, et al., Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate. Science. 2008 Jan 18;319(5861):304-9
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory