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Rgs13tm1Drue
Targeted Allele Detail
Nomenclature
Symbol: Rgs13tm1Drue
Name: regulator of G-protein signaling 13; targeted mutation 1, Kirk M Druey
MGI ID: MGI:3771964
Synonyms: Rgs13-
Gene: Rgs13  Location: Chr1:144138654-144177372 bp, - strand  Genetic Position: Chr1, 62.56 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130209
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 4 was replaced with a lacZ neo cassette. The absence of transcript in bone marrow-derived mast cells was confirmed by RT-PCR and the absence of protein in bone marrow-derived mast cells was confirmed by immunohistochemistry. (J:130209)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rgs13 Mutation:  5 strains or lines available
Notes
ES cell = iTL4 (129S6/SvEvTac)
References
Original:  J:130209 Bansal G, et al., Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13. Nat Immunol. 2008 Jan;9(1):73-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory