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Errfi1tm1Jwj
Targeted Allele Detail
Nomenclature
Symbol: Errfi1tm1Jwj
Name: ERBB receptor feedback inhibitor 1; targeted mutation 1, Jae-Wook Jeong
MGI ID: MGI:3769404
Synonyms: Errf1f, Mig-6flox
Gene: Errfi1  Location: Chr4:150853919-150868892 bp, + strand  Genetic Position: Chr4, 81.5 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129106
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4 and an additional loxP site was inserted upstream of exon 2. The neo cassette was subsequently removed by flp-mediated recombination. (J:129106)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Errfi1 Mutation:  10 strains or lines available
References
Original:  J:129106 Jin N, et al., Generation of a Mig-6 conditional null allele. Genesis. 2007 Nov;45(11):716-21
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory