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Tg(Lck-Jak3)2Ljb
Transgene Detail
Nomenclature
Symbol: Tg(Lck-Jak3)2Ljb
Name: transgene insertion 2, Leslie J Berg
MGI ID: MGI:3769343
Synonyms: Tgthy
Transgene: Tg(Lck-Jak3)2Ljb  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene expresses a murine Jak3 cDNA under the control of the Lck proximal promoter. Transgene expression is initially detected in the thymocytes and peripheral T cells but is gradually lost in peripheral T cells. (J:128694)
Phenotypes
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:128694 Thomis DC, et al., Peripheral expression of Jak3 is required to maintain T lymphocyte function. J Exp Med. 1997 Jan 20;185(2):197-206
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory