About   Help   FAQ
Scn1btm2.1Isom
Targeted Allele Detail
Nomenclature
Symbol: Scn1btm2.1Isom
Name: sodium channel, voltage-gated, type I, beta; targeted mutation 2.1, Lori L Isom
MGI ID: MGI:3768514
Synonyms: Scn1bdel
Gene: Scn1b  Location: Chr7:31116524-31127003 bp, - strand  Genetic Position: Chr7, 19.3 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128713
Parent Cell Line:  Pat5 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsScn1btm2Isom mice were mated with transgenic mice that ubiquitously express Cre to remove the floxed allele. Gene inactivation was demonstrated by western blot and by in situ hybridization of brain tissue. (J:128713)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scn1b Mutation:  4 strains or lines available
References
Original:  J:128713 Chen C, et al., Floxed allele for conditional inactivation of the voltage-gated sodium channel beta1 subunit Scn1b. Genesis. 2007 Sep;45(9):547-53
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/05/2019
MGI 6.14
The Jackson Laboratory