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Nanos2tm2Ysa
Targeted Allele Detail
Summary
Symbol: Nanos2tm2Ysa
Name: nanos C2HC-type zinc finger 2; targeted mutation 2, Yumiko Saga
MGI ID: MGI:3768176
Synonyms: nanos2L-3'UTR
Gene: Nanos2  Location: Chr7:18721449-18722887 bp, + strand  Genetic Position: Chr7, 9.45 cM
Alliance: Nanos2tm2Ysa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119032
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced with a lacZ cassette inserted at the start codon of the first coding exon. The 3' untranslated region was retained. A floxed neo cassette was inserted downstream of the coding region and was subsequently removed via cre mediated recombination. LacZ expression was detected in mutant mice. (J:119032)
Expression
In Mice Carrying this Mutation: 26 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nanos2 Mutation:  15 strains or lines available
References
Original:  J:119032 Tsuda M, et al., Implication of nanos2-3'UTR in the expression and function of nanos2. Mech Dev. 2006 Jun;123(6):440-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory