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Tg(Rgs4-EGFP)4Lvt
Transgene Detail
Nomenclature
Symbol: Tg(Rgs4-EGFP)4Lvt
Name: transgene insertion 4, Pat Levitt
MGI ID: MGI:3767843
Synonyms: R4BAC4, RGS4-BAC, RGS4-BAC line 4, RGS4 BAC transgenic, RGS4-GFP, RGS4 transgenic
Transgene: Tg(Rgs4-EGFP)4Lvt  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA C57BL/6J-derived bacterial artificial chromosome (BAC; RPCI-23-82i24) was modified by inserting an IRES2-eGFP construct (and an frt-flanked neomycin resistance cassette) into the 3' UTR of the Rgs4 locus. The neomycin cassette was subsequently removed by FLP-mediated recombination. Lines 3 and 4 were developed, and line 4 was entered as the representative transgenic allele. Under the control of the RGS4 promoter/enhancer elements, transgene expression reports dynamic developmental, regional, and cellular specific expression in developing and mature cerebral cortex neurons across all cortical domains, as well as developing and mature subcortical regions (telencephalon, diencephalon, and brainstem). (J:128689)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:128689 Ebert PJ, et al., Bacterial artificial chromosome transgenic analysis of dynamic expression patterns of regulator of G-protein signaling 4 during development. I. Cerebral cortex. Neuroscience. 2006 Nov 3;142(4):1145-61
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory