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Akap5tm2Gsm
Targeted Allele Detail
Nomenclature
Symbol: Akap5tm2Gsm
Name: A kinase (PRKA) anchor protein 5; targeted mutation 2, G Stanley Mcknight
MGI ID: MGI:3766311
Synonyms: AKAP150 -, AKAP150delta36
Gene: Akap5  Location: Chr12:76324891-76334153 bp, + strand  Genetic Position: Chr12, 33.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128208
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/SvImJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene was replaced with a neomycin phosphotransferase cassette. Immunoblotting of forebrain lysates from homozgyote mice confirmed gene inactivation. (J:128208)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Akap5 Mutation:  13 strains or lines available
References
Original:  J:128208 Hall DD, et al., Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry. 2007 Feb 13;46(6):1635-46
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory