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Targeted Allele Detail
Symbol: Akap5tm2Gsm
Name: A kinase (PRKA) anchor protein 5; targeted mutation 2, G Stanley Mcknight
MGI ID: MGI:3766311
Synonyms: AKAP150 -
Gene: Akap5  Location: Chr12:76324891-76334153 bp, + strand  Genetic Position: Chr12, 33.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:128208
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire coding region of the gene was replaced with a neomycin phosphotransferase cassette. Immunoblotting of forebrain lysates from homozgyote mice confirmed gene inactivation. (J:128208, J:160134)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Akap5 Mutation:  16 strains or lines available
Original:  J:128208 Hall DD, et al., Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry. 2007 Feb 13;46(6):1635-46
All:  13 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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