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Tg(HSA*LR)32aCath
Transgene Detail
Nomenclature
Symbol: Tg(HSA*LR)32aCath
Name: transgene insertion 32a, Charles A Thornton
MGI ID: MGI:3763909
Synonyms: LR32a, Tg(HSA*LR)32a
Transgene: Tg(HSA*LR)32aCath  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(HSA*LR)32aCath expresses 1 gene
 
Mutation detailsThe transgene contains human HSA with an expanded (250 repeats) CTG inserted into the last exon. Seven lines were created with expression restricted to skeletal muscle. This line contains 4 transgene insertions with expression levels that reached equivalent levels to HSA expression in human skeletal muscle. (J:64493)
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:64493 Mankodi A, et al., Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat [see comments]. Science. 2000 Sep 8;289(5485):1769-73
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory