About   Help   FAQ
Tacc3tm1.2Tno
Targeted Allele Detail
Nomenclature
Symbol: Tacc3tm1.2Tno
Name: transforming, acidic coiled-coil containing protein 3; targeted mutation 1.2, Tetsuo Noda
MGI ID: MGI:3763219
Synonyms: Tacc3D
Gene: Tacc3  Location: Chr5:33658128-33672203 bp, + strand  Genetic Position: Chr5, 17.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:126471
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe genomic region between intron 4 and 5 was removed by cre-mediated recombination following the electroporation of embryonic stem cells with a transient cre-expression construct. The absence of protein product was confirmed by western blot analysis on protein extracted from whole E9.5 embryos. (J:126471)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tacc3 Mutation:  11 strains or lines available
References
Original:  J:126471 Yao R, et al., TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton. Cancer Sci. 2007 Apr;98(4):555-62
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/03/2020
MGI 6.15
The Jackson Laboratory