About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Targeted Allele Detail
Symbol: Emx1tm1.1(cre)Ito
Name: empty spiracles homeobox 1; targeted mutation 1.1, Shigeyoshi Itohara
MGI ID: MGI:3762664
Synonyms: Emx1-Cre KI deltaneo, Emx1tm2(cre)Ito
Gene: Emx1  Location: Chr6:85187438-85204462 bp, + strand  Genetic Position: Chr6, 37.21 cM
Germline Transmission:  Earliest citation of germline transmission: J:88421
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
Mutation detailsA cDNA encoding Cre recombinase with an N-terminal nuclear localization signal (nls) resides immediately 5' of the translation initiation site of the endogenous gene. This allele was derived from Emx1tm1(cre)Ito by FLP recombinase excision of a FRT-flanked pgk-neo cassette that lay immediately downstream of the nls-cre gene. The Emx1 promoter drives Cre recombinase expression in the embryonic through adult dorsal telencephelon; deletion of the selection cassette reportedly prevents ectopic expression in other brain regions. (J:64064, J:104881)
 Tissue activity of this recombinase allele
Driver: Emx1     Summary of all recombinase alleles driven by Emx1.

View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Emx1 Mutation:  12 strains or lines available
Original:  J:88421 Iwasato T, et al., Dorsal telencephalon-specific expression of Cre recombinase in PAC transgenic mice. Genesis. 2004 Mar;38(3):130-8
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory