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Gene trapped Allele Detail
Symbol: Git2Gt(XG510)Byg
Name: GIT ArfGAP 2; gene trap XG510, BayGenomics
MGI ID: MGI:3762635
Synonyms: GIT2-
Gene: Git2  Location: Chr5:114727408-114774588 bp, - strand  Genetic Position: Chr5, 55.99 cM
Mutant Cell Line:  XG510
Germline Transmission:  Earliest citation of germline transmission: J:126878
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped (Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
Mutation detailsA gene trap vetor containing a beta-geo cassette was inserted into intron 2. Insertion was confirmed by PCR genotyping and expression of the lacZ gene was confirmed by beta-galactosidase staining. Two transcripts were detected by RT-PCR: one the expected fusion of exon 1 and 2 to the gene trap vector sequence and the other an alternative transcript lacking exon 2. (J:126878)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Git2 Mutation:  22 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:126878 Schmalzigaug R, et al., Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues. J Histochem Cytochem. 2007 Oct;55(10):1039-48
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory