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Tg(KRT14-rtTA)F42Efu
Transgene Detail
Nomenclature
Symbol: Tg(KRT14-rtTA)F42Efu
Name: transgene insertion F42, Elaine Fuchs
MGI ID: MGI:3762564
Synonyms: K14rtTA, K14-rtTA
Transgene: Tg(KRT14-rtTA)F42Efu  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsA transgenic vector incorporating the human keratin 14 promoter/enhancer, rabbit beta globin 5' untranslated region (UTR) for stabilization of transcript, the reverse tetracycline regulatable transactivator protein (rtTA2S-M2-VP16), and the keratin 14 3' UTR was injected into FVB embryos. (J:56822, J:116057)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:116057 Nguyen H, et al., Tcf3 governs stem cell features and represses cell fate determination in skin. Cell. 2006 Oct 6;127(1):171-83
All:  41 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory