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Il1rl2tm1Hblu
Targeted Allele Detail
Nomenclature
Symbol: Il1rl2tm1Hblu
Name: interleukin 1 receptor-like 2; targeted mutation 1, Hal Blumberg
MGI ID: MGI:3762029
Synonyms: IL1RL2-, IL-1Rrp2-, IL-36R-
Gene: Il1rl2  Location: Chr1:40324610-40367562 bp, + strand  Genetic Position: Chr1, 18.96 cM
Il1rl2tm1Hblu/Il1rl2tm1Hblu and Il1f5tm1Kopf/Il1f5tm1Kopf mice show different susceptibilities to IMQ-induced psoriasiform dermatitis

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:126327
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 4 were replaced with a lacZ-neo cassette. Insertion was confirmed by Southern blot analysis. (J:126327)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il1rl2 Mutation:  1 strain or line available
References
Original:  J:126327 Blumberg H, et al., Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. J Exp Med. 2007 Oct 29;204(11):2603-14
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory