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Transgenic Allele Detail
Symbol: Lrfn2Tg(CD2-Myb/en)5Kmw
Name: leucine rich repeat and fibronectin type III domain containing 2; transgene insertion 5, Kathleen Mary Weston
MGI ID: MGI:3761369
Synonyms: MEnT5, MEnTCD2.5
Gene: Lrfn2  Location: Chr17:48932379-49097588 bp, + strand  Genetic Position: Chr17, 24.66 cM, cytoband C
Strain of Origin:  (CBA x C57BL/10)F1
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Lrfn2Tg(CD2-Myb/en)5Kmw expresses 1 gene
Mutation detailsA transgene containing the human CD2 promoter driving the expression of an in-frame fusion of mouse Myb and amino acids 2-298 of Drosophila engrailed was randomly inserted in reverse orientation within the first intron. The insertion leads to an increase in expression of a normal transcript. Insertion was confirmed by Sourthern blot analysis. (J:125805, J:126456)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrfn2 Mutation:  32 strains or lines available
Original:  J:126456 Badiani P, et al., Dominant interfering alleles define a role for c-Myb in T-cell development. Genes Dev. 1994 Apr 1;8(7):770-82
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
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