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Ankrd23tm1Krc
Targeted Allele Detail
Nomenclature
Symbol: Ankrd23tm1Krc
Name: ankyrin repeat domain 23; targeted mutation 1, Kenneth R Chien
MGI ID: MGI:3760785
Gene: Ankrd23  Location: Chr1:36530188-36536883 bp, - strand  Genetic Position: Chr1, 15.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125819
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first 3 exons were replaced by cDNA encoding lacZ and a pGK neo cassette, bringing the beta-galactosidase cDNA under the control of the endogenous promoter while ablating the endogenous gene. Northern and Western blot analysis on skeletal muscle and heart confirmed absence of Ankrd2 RNA and protein, respectively. (J:125819, J:215212)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ankrd23 Mutation:  3 strains or lines available
References
Original:  J:125819 Barash IA, et al., Structural and regulatory roles of muscle ankyrin repeat protein family in skeletal muscle. Am J Physiol Cell Physiol. 2007 Jul;293(1):C218-27
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory