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Targeted Allele Detail
Symbol: Gnao1tm1Adhi
Name: guanine nucleotide binding protein, alpha O; targeted mutation 1, Anuradha Dhingra
MGI ID: MGI:3759767
Synonyms: Galphao1
Gene: Gnao1  Location: Chr8:93810561-93969388 bp, + strand  Genetic Position: Chr8, 45.94 cM
Germline Transmission:  Earliest citation of germline transmission: J:125588
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 7.1 was replaced with a neo cassette and an IRES-lacZ cassette. Western blot analysis was used to confirm the expression of the protein as a 43 kDa band in retinal extracts. (J:125588)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gnao1 Mutation:  4 strains or lines available
Original:  J:125588 Dhingra A, et al., Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o). J Neurosci. 2002 Jun 15;22(12):4878-84
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory