Tg(Spry2)2Tpo
Transgene Detail

Summary

• Symbol: Tg(Spry2)2Tpo
• Name: transgene insertion 2, Timothy P O'Brien
• MGI ID: MGI:3759546
• Synonyms: Spry2-BAC-2, Spry2-Tg-2
• Transgene: Tg(Spry2)2Tpo Location: unknown
• Alliance: Tg(Spry2)2Tpo page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Spry2)2Tpo expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Spry2 (MGI:1345138)

• Mutation details: An 80kb BAC encoding the Spry2 locus was isolated from a CITB-CJ7 (129S1/Sv) BAC library. Southern blot analysis determined a copy number of 1-2 for line 2. RT-PCR analysis of E14.5 embryonic palate tissue showed that line 2 expressed the transgenic Spry2 at ~12.5% of wild-type levels. (J:125229)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:125229 Welsh IC, et al., A dosage-dependent role for Spry2 in growth and patterning during palate development. Mech Dev. 2007 Sep-Oct;124(9-10):746-61
• All: 1 reference(s)