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Targeted Allele Detail
Symbol: Zfp704tm1Glh
Name: zinc finger protein 704; targeted mutation 1, David J Goldhamer
MGI ID: MGI:3759307
Synonyms: Gig1nlacZ
Gene: Zfp704  Location: Chr3:9427020-9610085 bp, - strand  Genetic Position: Chr3, 2.31 cM
Germline Transmission:  Earliest citation of germline transmission: J:125184
Parent Cell Line:  D1 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6J)F1
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA lacZ-3pA with a nuclear localization signal and a floxed PGKneo cassette were inserted into exon 1 to create a null allele. Removal of the cre cassette was achieve via a cross to mice carrying the Hprt1tm1(cre)Mnn allele. Absence of transcript was confirmed by RT-PCR on homozygous mice. LacZ expression was confirmed by X-gal staining. (J:125184)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 82 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfp704 Mutation:  30 strains or lines available
Original:  J:125184 Yamamoto M, et al., Cloning and characterization of a novel MyoD enhancer-binding factor. Mech Dev. 2007 Sep-Oct;124(9-10):715-28
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory