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Foxp2tm1.2Sfis
Targeted Allele Detail
Nomenclature
Symbol: Foxp2tm1.2Sfis
Name: forkhead box P2; targeted mutation 1.2, Simon E Fisher
MGI ID: MGI:3723630
Synonyms: Foxp2delta12-14
Gene: Foxp2  Location: Chr6:14901388-15441201 bp, + strand  Genetic Position: Chr6, 6.49 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125023
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 12 through 14 were removed by cre-mediated recombination. The absence of protein product was confirmed by western blot analysis on the striatal precursor region of E16.5 embryos using antibodies recognizing the N-terminal region of the protein. (J:125023)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 16 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp2 Mutation:  28 strains or lines available
References
Original:  J:125023 French CA, et al., Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory