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Transgene Detail
Symbol: Tg(Eno2-YFP/Cox8a)ZRwb
Name: transgene insertion Z, Robert Burgess
MGI ID: MGI:3722777
Synonyms: 401, MitoZ
Transgene: Tg(Eno2-YFP/Cox8a)ZRwb  Location: unknown  
Strain of Origin:  C57BL/6J
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsA transgenic construct containing the entire open reading frame of the Yellow Fluorescent Protein gene fused in-frame with the mitochondrial targeting sequence of the mouse cytochrome c oxidase, subunit VIIIa, gene under the direction of regulatory elements derived from the rat enolase 2, gamma gene, Eno2, was injected into fertilized C57BL/6J donor mouse eggs. Founder line Z was established. YFP is specifically localized to the mitochondria by a mouse cytochrome c oxidase, subunit VIIIa, gene targeting signal fused to the N-terminus. Fluorescence is detected in many neuronal populations. (J:122259)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:122259 Misgeld T, et al., Imaging axonal transport of mitochondria in vivo. Nat Methods. 2007 Jul;4(7):559-561
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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