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Ppp1r16btm1Ccb
Targeted Allele Detail
Nomenclature
Symbol: Ppp1r16btm1Ccb
Name: protein phosphatase 1, regulatory subunit 16B; targeted mutation 1, Conrad C Bleul
MGI ID: MGI:3722113
Gene: Ppp1r16b  Location: Chr2:158666733-158766334 bp, + strand  Genetic Position: Chr2, 78.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:124347
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting construct was designed to replace 643 nucleotides of sequence corresponding to nucleotides 59952 to 60594 of AL663077 that encode exon 4 by a neomycin resistance cassette. A mutant mRNA, reduced by the size of exon 4, was detected. (J:124347)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppp1r16b Mutation:  2 strains or lines available
References
Original:  J:124347 Heinzel K, et al., The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis. Eur J Immunol. 2007 Sep;37(9):2562-71
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory