Angptl1^tm1Hung
Targeted Allele Detail

Summary

• Symbol: Angptl1^tm1Hung
• Name: angiopoietin-like 1; targeted mutation 1, Hung Li
• MGI ID: MGI:3721928
• Gene: Angptl1 Location: Chr1:156666495-156688648 bp, + strand Genetic Position: Chr1, 67.75 cM, cytoband G3
• Alliance: Angptl1^tm1Hung page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124184
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a nuclear LacZ reporter gene and a neomycin selection cassette. No endogenous gene expression was observed in homozygous mice, as determined by RT PCR on several tissues. LacZ staining was observed in the nuclei of cells from the intermuscular fascia of homozygous late stage embryos. (J:124184)

Expression

In Mice Carrying this Mutation:

56 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl1 Mutation: 30 strains or lines available

References

• Original: J:124184 Lai DM, et al., Angiopoietin-like protein 1 expression is related to intermuscular connective tissue and cartilage development. Dev Dyn. 2007 Sep;236(9):2643-52
• All: 1 reference(s)