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Targeted Allele Detail
Symbol: Zbtb17tm1Cksn
Name: zinc finger and BTB domain containing 17; targeted mutation 1, Christian Kosan
MGI ID: MGI:3721142
Synonyms: Miz-1flox, Mizllox, Zbtb17fldeltaneo
Gene: Zbtb17  Location: Chr4:141444654-141467930 bp, + strand  Genetic Position: Chr4, 74.17 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:123966
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsExons 3 and 4, encoding the POZ/BTB domain, were flanked by loxP sites. A floxed neo cassette inserted downstream of exon 4 was removed by cre-mediated recombination. (J:123966, J:167721)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zbtb17 Mutation:  6 strains or lines available
Original:  J:123966 Gebhardt A, et al., Miz1 is required for hair follicle structure and hair morphogenesis. J Cell Sci. 2007 Aug 1;120(Pt 15):2586-93
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory