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Capn10tm1Ksp
Targeted Allele Detail
Nomenclature
Symbol: Capn10tm1Ksp
Name: calpain 10; targeted mutation 1, Kenneth S Polonsky
MGI ID: MGI:3721096
Synonyms: Capn10-
Gene: Capn10  Location: Chr1:92934376-92947941 bp, + strand  Genetic Position: Chr1, 46.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123988
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to delete exon 2. The vector included the self excising ACN cassette. Western blot confirmed absence of protein in mutants. (J:123988)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Capn10 Mutation:  9 strains or lines available
References
Original:  J:123988 Johnson JD, et al., RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 4;279(23):24794-802
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory