About   Help   FAQ
F12tm1Pbfd
Targeted Allele Detail
Nomenclature
Symbol: F12tm1Pbfd
Name: coagulation factor XII (Hageman factor); targeted mutation 1, Peter Burfiend
MGI ID: MGI:3720935
Synonyms: FXII-
Gene: F12  Location: Chr13:55417958-55426793 bp, - strand  Genetic Position: Chr13, 30.06 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:124154
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were replaced with a neomycin resistance cassette. Northern blot analysis confirmed absence of protein in mutant mice. (J:124154)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any F12 Mutation:  11 strains or lines available
References
Original:  J:124154 Pauer HU, et al., Targeted deletion of murine coagulation factor XII gene-a model for contact phase activation in vivo. Thromb Haemost. 2004 Sep;92(3):503-8
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory