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Atf7tm1Nicj
Targeted Allele Detail
Nomenclature
Symbol: Atf7tm1Nicj
Name: activating transcription factor 7; targeted mutation 1, Nic Jones
MGI ID: MGI:3720869
Synonyms: Atf7-
Gene: Atf7  Location: Chr15:102525946-102625464 bp, - strand  Genetic Position: Chr15, 57.66 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123909
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to insert an IRES-lacZ-pA and floxed neo into the locus, replacing part of exon 10 which encodes the basic region DNA binding domain and part of the leucine zipper dimerization domain. (J:123909)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atf7 Mutation:  41 strains or lines available
References
Original:  J:123909 Breitwieser W, et al., Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells. Genes Dev. 2007 Aug 15;21(16):2069-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory