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Aicdatm172Mnz
Targeted Allele Detail
Nomenclature
Symbol: Aicdatm172Mnz
Name: activation-induced cytidine deaminase; targeted mutation 172, Michel C Nussenzweig
MGI ID: MGI:3720569
Synonyms: AIDF, Flag AID
Gene: Aicda  Location: Chr6:122530768-122541139 bp, + strand  Genetic Position: Chr6, 57.65 cM, cytoband F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167917
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked selection cassette was inserted between exons 1 and 2, and a tandem FLAG and hemagglutinin (HA) tag was inserted at the start site in exon 1. Flp-mediated recombination removed the neo cassette. (J:167917)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aicda Mutation:  49 strains or lines available
References
Original:  J:167917 Pavri R, et al., Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell. 2010 Oct 1;143(1):122-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory