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Mapttm1Aha
Targeted Allele Detail
Nomenclature
Symbol: Mapttm1Aha
Name: microtubule-associated protein tau; targeted mutation 1, Akihiro Harada
MGI ID: MGI:3720198
Synonyms: tau-
Gene: Mapt  Location: Chr11:104231390-104332090 bp, + strand  Genetic Position: Chr11, 67.79 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123734
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn frt-flanked pgk-neo was inserted to replace exon 1 in reverse orientation. Western blot confirmed absence of transcript in mutant brain samples. (J:123734)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapt Mutation:  401 strains or lines available
References
Original:  J:123734 Fujio K, et al., 14-3-3 proteins and protein phosphatases are not reduced in tau-deficient mice. Neuroreport. 2007 Jul 2;18(10):1049-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory