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Targeted Allele Detail
Symbol: Del(11Cxcl16-Zmynd15)1Ifc
Name: deletion, Chr 11, Israel F Charo
MGI ID: MGI:3720171
Synonyms: Cxcl16-, Cxcl16tm1Ifc, Cxcl16/Zmynd15tm1Ifc
Gene: Del(11Cxcl16-Zmynd15)1Ifc  Location: unknown  Genetic Position: Chr11, Syntenic
Spermatogenic disruption in the testes of Del(11Cxcl16-Zmynd15)1Ifc/Del(11Cxcl16-Zmynd15)1Ifc mice

Show the 4 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:123851
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
  Del(11Cxcl16-Zmynd15)1Ifc involves 2 genes/genome features (Cxcl16, Zmynd15) View all
Mutation detailsA neomycin resistance cassette replaced the entire coding sequence of Cxcl16 and a portion of the overlapping 5'UTR of Zmynd15. Quantitative RT-PCR confirmed the absence of both transcripts. (J:123851)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(11Cxcl16-Zmynd15)1Ifc Mutation:  0 strains or lines available
Original:  J:123851 Aslanian AM, et al., Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerosis. Circulation. 2006 Aug 8;114(6):583-90
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
The Jackson Laboratory