About   Help   FAQ
Ldb1tm2Lmgd
Targeted Allele Detail
Nomenclature
Symbol: Ldb1tm2Lmgd
Name: LIM domain binding 1; targeted mutation 2, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID: MGI:3719683
Synonyms: Ldb1fl
Gene: Ldb1  Location: Chr19:46032589-46045515 bp, - strand  Genetic Position: Chr19, 38.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123471
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of the coding region and a floxed neo cassette was inserted into the ninth intron. In vivo cre mediated recombination removed the neo cassette leaving a single loxP site in the ninth intron (J:123471)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ldb1 Mutation:  29 strains or lines available
References
Original:  J:123471 Zhao Y, et al., LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13182-6
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory