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Spi1tm1Rpd
Targeted Allele Detail
Nomenclature
Symbol: Spi1tm1Rpd
Name: spleen focus forming virus (SFFV) proviral integration oncogene; targeted mutation 1, Rodney P DeKoter
MGI ID: MGI:3717917
Synonyms: Sfpi1BN
Gene: Spi1  Location: Chr2:91082390-91115756 bp, + strand  Genetic Position: Chr2, 50.44 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123079
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace both translation start sites with beta-lactamase and a floxed PGK-neo. (J:123079)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spi1 Mutation:  12 strains or lines available
References
Original:  J:123079 Houston IB, et al., Reduction in PU.1 activity results in a block to B-cell development, abnormal myeloid proliferation, and neonatal lethality. Exp Hematol. 2007 Jul;35(7):1056-68
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory