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Il31ratm1Ngh
Targeted Allele Detail
Nomenclature
Symbol: Il31ratm1Ngh
Name: interleukin 31 receptor A; targeted mutation 1, Nico Ghilardi
MGI ID: MGI:3717594
Synonyms: Il-13ralpha
Gene: Il31ra  Location: Chr13:112522810-112580662 bp, - strand  Genetic Position: Chr13, 63.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123198
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5-8, which encode the ligand-binding cytokine receptor homology domain, were replaced with a neomycin resistance cassette. Absence of expression was confirmed by quantitative Taqman PCR. (J:123198)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il31ra Mutation:  42 strains or lines available
References
Original:  J:123198 Perrigoue JG, et al., IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. J Exp Med. 2007 Mar 19;204(3):481-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory