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Lynx1tm1Htz
Targeted Allele Detail
Summary
Symbol: Lynx1tm1Htz
Name: Ly6/neurotoxin 1; targeted mutation 1, Nathaniel Heintz
MGI ID: MGI:3716630
Synonyms: Lynx1-
Gene: Lynx1  Location: Chr15:74619705-74624828 bp, - strand  Genetic Position: Chr15, 34.27 cM
Alliance: Lynx1tm1Htz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122965
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding sequence was replaced with a neomycin resistance cassette. Western blot confirmed absence of protein in mutants. (J:122965)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lynx1 Mutation:  10 strains or lines available
References
Original:  J:122965 Miwa JM, et al., The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 2006 Sep 7;51(5):587-600
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/15/2022
MGI 6.22
The Jackson Laboratory